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Whole Exome Data Analysis for Identification of DNA Polymorphism [ 3 DAYS]

Course Code : BWEDA01G


This 3 day course would provide hands on and theoretical knowledge to the participant about how to analyze deep sequencing data obtained by targetecturd re-sequencing of genome sequenced using Illumina Platform.   This course also will give indepth understanding of qualitative and quantitative measurement of Single Nucleotide Variations and Stuctural variations in an individual as compared to the reference human genome.

Research Scholars / Graduate Students / Faculties who are working on population genetics / clinical genomics segment who are applying or indenting to use deep sequencing approach for whole exome or targeted resequencing using Illumina Platform.



Basic working knowledge on computer (Preference to be given for those exposed to Linux Operating System).


a) To ensure participant to confidently handle whole exome / targeted re-sequencing data at beginner level.
b) To give experience to the participant on performing analysis of whole exome / targeted re-sequencing data starting from raw data  quality control till identification of Single Nucleotide Variations / Structural Variations in an Individual as compared to the reference genome.
c) To enable participant to gain command over linux operating system for analysis of deep sequencing data.
 a) Introduction to deep sequencing of Exome/Targeted Regions using Illumina Platform
 b) Experimental Designs and Quality Control measures for a successful Exome sequencing study
 c) Introduction to Illumina based deep sequencing raw data and its quality control
 d) Alignment of High Quality (QC Passed) raw data to reference genome and its quality control
 e) Exome / Target Enrichment Analysis & Quality Control
 f) Genetic / Structural Variation Calling & Quality Control
 g) Variation Annotation, Classification & Functional Impact Analysis
 h) Various Possible downstream bioinformatics analysis towards discovery and translational research
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Start Date End Date Country Location Register
28 January 2019 30 January 2019 Singapore